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Cytoplasmic granules turn dark when stained with chromic acid because of the oxidation of epinephrine and norepinephrine to melanin. However, full differentiation of the permanent cortex into the three zones of the adult gland glomerulosa, fasciculata, and reticularis is not completed until about the third year after birth. Texts Video icon An illustration of two cells of a film strip. The site of action of vasopressin is the V2 receptor on the epithelial principal cells of the collecting ducts. Netter, MD, and Carlos A.
